DONEP M FORTE Tablet 15's is a medication that combines the drugs Donepezil and Memantine, which are both acetylcholinesterase inhibitors and NMDA receptor antagonists, respectively. It is used to treat Alzheimer's disease-related dementia (Alzheimer's type dementia) in individuals who have previously received donepezil alone. Alzheimer's type dementia is a form of brain disease in which the dementia (abnormalities in thinking, memory, and behaviour) are brought on by the ageing of memory-carrying brain cells. Acetylcholinesterase inhibitor donepezil is used. It works by raising the amounts of acetylcholine, a substance that transmits messages between nerve cells in the brain. An antagonist of the NMDA receptor is memantine. It works by preventing the overactivation of specific brain chemicals (such as glutamate) that harms nerve cells.Disclaimer:For more information contact your physician.